Archives of Disease in Childhood - Fetal and Neonatal Edition PostScript http://fn.bmj.com Archives of Disease in Childhood - Fetal and Neonatal Edition RSS feed -- recent PostScript articles 1468-2052 Archives of Disease in Childhood - Fetal and Neonatal Edition 1359-2998 Archives of Disease in Childhood - Fetal and Neonatal Edition http://hwmaint.fn.bmj.com/misc/home/ADC_95x60.gif http://fn.bmj.com <![CDATA[Movement of peripherally inserted central catheters in relation to limb movement in neonates: a prospective observational study]]> http://fn.bmj.com/cgi/content/short/111/3/F286?rss=1 Peripherally inserted central catheters (PICCs) are commonly used in the neonatal population. There are complications of PICC insertion; therefore, accurate placement of PICCs is essential. The literature suggests that arm limb movements significantly affect the position of the tip of the PICCs;1 however, currently, there is no published data describing how much catheters move in relation to limb movement.

We conducted a prospective observational study to understand PICC movement in relation to limb position in real time. Neonates admitted to a tertiary neonatal unit, at St George’s Hospital, London, needing point of care ultrasound (POCUS) to confirm optimal PICC position were included. The ultrasound scans were performed by a single operator (AMK) with formal training in paediatric echocardiography. All the assessments were done using multiphased array, curvilinear and linear probes with GE S70 Ultrasound machine. The images were stored on the Philips IntelliSpace PACS system. We used...]]> 2026-04-17T00:45:42-07:00 info:doi/10.1136/archdischild-2025-328992 hwp:master-id:fetalneonatal;archdischild-2025-328992 BMJ Publishing Group 2026-05-01 PostScript 111 3 F286 F286 <![CDATA[Trials of medications for neonatal seizures: time for pragmatism]]> http://fn.bmj.com/cgi/content/short/111/3/F286-a?rss=1 Despite there being many randomised controlled trials (RCTs) of anticonvulsants in children and adults, there are only two RCTs directly comparing anticonvulsants in neonatal seizures.1 2 Acknowledging this inequality, the James Lind Alliance has highlighted neonatal seizures treatments as a top research priority.3 Why so few trials exist is an important question. One explanation may be the recommendation that continuous multichannel electroencephalogram (cEEG) should be the outcome measure of choice because of its superior detection rates compared with amplitude integrated EEG (aEEG).4 This is important because most neonatal seizures are electrographic and over-diagnosis of seizures in response to other movements is common. While scientifically justified, cEEG is not available or interpretable at all hours of the day in all UK Neonatal Units.

The NEOLEV2 study emphasised that, ‘the end point of greatest concern in neonatal seizure trials is long-term neurodevelopmental outcome....]]> 2026-04-17T00:45:42-07:00 info:doi/10.1136/archdischild-2025-329844 hwp:master-id:fetalneonatal;archdischild-2025-329844 BMJ Publishing Group 2026-05-01 PostScript 111 3 F286 F288